![]() ![]() It is well recognized that RT-induced VS may have negative impacts on patient well-being, in particular sexual dysfunction and dyspareunia and implications for limiting physical examination in the posttreatment surveillance period. ![]() 1, 2 VS may occur following external beam radiation therapy (EBRT) or brachytherapy or both delivered in the definitive, adjuvant or palliative setting. A commonly observed side effect of pelvic RT is radiation-induced vaginal stenosis (VS), defined as abnormal tightening and shortening of the vagina due to the formation of fibrosis. Treatment of uterine, cervical, vaginal and anorectal cancers commonly involves pelvic radiation therapy (RT). Keywords: gynecological cancer, radiation therapy, vaginal stenosis, brachytherapy, vaginal dilators The limited available literature on many of these aspects suggests that additional studies are required to more precisely determine the best management strategy of this prevalent group after RT. In addition, risk factors, prevention and treatment options and follow-up schedules are also discussed. This review analyzed the incidence, pathogenesis, clinical manifestation(s) and assessment and grading of radiation-induced VS. A commonly observed side effect of such treatment is radiation-induced vaginal stenosis (VS). ![]() Lucinda Morris, 1 Viet Do, 1 Jennifer Chard, 1 Alison H Brand 2,3ġCrown Princess Mary Cancer Centre Westmead, Radiation Oncology Network, Westmead, 2Discipline of Obstetrics, Gynaecology and Neonatology, Westmead Clinical School, University of Sydney, Camperdown, 3Department of Gynaecological Oncology, Westmead Hospital, Westmead, NSW, AustraliaĪbstract: Treatment of gynecological cancer commonly involves pelvic radiation therapy (RT) and/or brachytherapy. ![]()
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